Painel Brasileiro da Obesidade
Ficha da publicação
Nome da publicação: Role of Planetary Health Diet in the association between genetic susceptibility to obesity and anthropometric measures in adults
Autores: Tiina Suikki, Mirkka Maukonen, Heidi Marjonen-Lindblad, Niina Erika Kaartinen, Tommi Härkänen, Pekka Jousilahti, Anne-Maria Pajari, Satu Männistö
Fonte: International Journal of Obesity
Publicado em: 2025
Tipo de arquivo: Artigo de periódico
Background/Objective The roles of overall diet quality in linking genetic background with anthropometric measures are unclear, particularly regarding the recently developed Planetary Health Diet (PHD). This study aims to determine if the PHD mediates or moderates the relationship between genetic susceptibility to obesity and anthropometric measures. Results PRS for BMI was positively associated with baseline BMI and changes in anthropometric measures, except waist circumference (p = 0.12). Significant associations were observed for baseline BMI and WC (p < 0.001), changes in BMI and WC (p = 0.01), and body fat percentage change (p = 0.05). However, the PHD (average score 3.8 points) did not mediate or moderate these relationships. These findings were consistent in the replication cohort. Conclusion Diet quality assessed with the PHD did not mediate or moderate the associations between genetic susceptibility to obesity and anthropometric measures. This lack of effect may be partly due to low adherence to the PHD and the older age of participants ( > 50 years) at baseline.