Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity

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Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity

Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity
2024
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Nome da publicação: Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity

Autores: Talyia M. Fordham, Nazeen S. Morelli, Yesenia Garcia‐Reyes, Meredith A. Ware, Haseeb Rahat, Divya Sundararajan, Kelly N. Z. Fuller, Cameron Severn, Laura Pyle, Craig R. Malloy, Eunsook S. Jin, Elizabeth J. Parks, Robert R. Wolfe, Melanie G. Cree

Fonte: Obesity

Publicado em: 2024

Tipo de arquivo: Artigo de periódico

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Resumo

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism,insulin resistance, and hepatic steatosis (HS). Because dietary essential amino acid(EAA) supplementation has been shown to decrease HS in various populations, thisstudy’s objective was to determine whether supplementation would decrease HSin PCOS. Similar to studies in older adults, short-term EAA supplementation inadolescents resulted in significantly lower liver fat, AST, and plasma lipids and thusmay prove to be an effective treatment in this population. Additional research isneeded to elucidate the mechanisms for these effects.