Painel Brasileiro da Obesidade
Publication sheet
Nome da publicação: Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity
Authors: Talyia M. Fordham, Nazeen S. Morelli, Yesenia Garcia‐Reyes, Meredith A. Ware, Haseeb Rahat, Divya Sundararajan, Kelly N. Z. Fuller, Cameron Severn, Laura Pyle, Craig R. Malloy, Eunsook S. Jin, Elizabeth J. Parks, Robert R. Wolfe, Melanie G. Cree
Source: Obesity
Published in: 2024
File type: Artigo de periódico
Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism,insulin resistance, and hepatic steatosis (HS). Because dietary essential amino acid(EAA) supplementation has been shown to decrease HS in various populations, thisstudy’s objective was to determine whether supplementation would decrease HSin PCOS. Similar to studies in older adults, short-term EAA supplementation inadolescents resulted in significantly lower liver fat, AST, and plasma lipids and thusmay prove to be an effective treatment in this population. Additional research isneeded to elucidate the mechanisms for these effects.